MIR211 (microRNA 211)

Chapter 5 MIRN 211 ( microRNA 211 )

Chapter 3 MIRN 211 ( microRNA 211 )

MicroRNA-211 suppresses prostate cancer proliferation by targeting SPARC

Dysregulation of microRNAs (miRNAs/miRs) is frequently associated with cancer progression. Altered expression of miR-211 has been observed in various types of human cancer; however, its expression and role in prostate cancer (PCa) remains unknown. In the present study, the expression of miR-211 in PCa cell lines and tissues was measured by reverse transcription-quantitative PCR (qPCR), revealin...

211 O'Donoghue.qxd

Background. Few studies have measured, using validated scales, the psychosocial handicap of epilepsy in a general practice setting. Aim. To assess the prevalence of psychosocial problems associated with epilepsy. Method. A survey was undertaken of 309 subjects, with one or more non-febrile epileptic seizures, drawn from two general practices in the United Kingdom (UK). The outcome measures were...

High-Throughput MicroRNA (miRNAs) Arrays Unravel the Prognostic Role of MiR-211 in Pancreatic Cancer

BACKGROUND Only a subset of radically resected pancreatic ductal adenocarcinoma (PDAC) patients benefit from chemotherapy, and identification of prognostic factors is warranted. Recently miRNAs emerged as diagnostic biomarkers and innovative therapeutic targets, while high-throughput arrays are opening new opportunities to evaluate whether they can predict clinical outcome. The present study ev...